emp17 peptide EMP17 peptide - Cerebrolysinpeptide peptide Understanding EMP17 Peptide: A Deep Dive into this Erythropoietin Mimetic

HMGpeptide The emp17 peptide, also known as Erythropoietin-Mimetic Peptide 17 (EMP17), is a synthetic molecule designed to mimic the actions of erythropoietin (EPO). Erythropoietin is a crucial hormone naturally produced by the kidneys that plays a vital role in stimulating the production of red blood cells in the bone marrow. This process, known as erythropoiesis, is essential for oxygen transport throughout the bodyErythropoietin-Mimetic Peptide 17 (EMP17) Supplier. Understanding the function and applications of EMP17 peptide requires exploring its nature as a peptide, its relationship to erythropoietin, and its potential uses in research and beyond.

EMP17 Peptide: The Science Behind the Mimicry

As a mimetic peptide, EMP17 is engineered to interact with the erythropoietin receptor (EPO-R) on the surface of target cells, much like endogenous erythropoietin. The primary mechanism involves EMP17 binding to the extracellular domain of the EPO-R. This binding event is believed to initiate a signaling cascade within the cell, ultimately leading to the stimulation of erythropoiesis. While erythropoietin is a glycoprotein hormone, EMP17 peptide is a smaller, synthetic peptide sequence that achieves a similar biological outcome. This makes it a valuable tool for researchers studying the intricacies of EPO signaling and receptor activationErythropoietin: Production, Purpose, Test & Levels - Cleveland Clinic.

The molecular structure of EMP17 peptide is often described by its amino acid sequence, such as TYSCHFGPLTWVCKPQGG. This sequence is critical for its ability to bind to the EPO receptor. Variations in this sequence, or modifications like FITC-LC labeled EMP17, are also available for specific research applications, such as fluorescence microscopy or binding assays. The molecular weight of EMP17 can vary slightly depending on its exact form and labeling, but it is generally in the range of approximately 2000-2500 DaltonsThis is a fluorescent (FITC)-labeled Erythropoietin (EPO)-mimeticpeptide(EMP17), Abs/Em=494/520 nm. Technical Data: M.Wt: 2483.9. For instance, one source indicates a molecular weight of 2483Tube of EMP17 peptide Tube of EMP17 peptide.9 for the FITC-LC labeled version, while another lists 1981.4 for the unconjugated form. Purity levels for EMP17 peptide are typically high, often reported as ≥95%, with options for 80%, 90%, 95%, 98%, 99% purity depending on the supplier and intended use.Peptidecoupling efficiency. Fluor-labeledpeptides(CaM Kinase II Substrate andEMP17) were from Anaspec. For cysteine coupling,peptideswere reconstituted at ...

Applications and Research Areas for EMP17 Peptide

The primary utility of EMP17 peptide lies in its role as a research chemical. Scientists utilize it to:

* Investigate EPO Receptor Binding: By studying how EMP17 interacts with the EPO-R, researchers can gain deeper insights into the structural requirements for receptor activation. This includes understanding the specific motifs involved in erythropoietin-receptor engagement.

* Study Erythropoiesis in vitro: EMP17 peptide can be used in cell culture experiments to stimulate red blood cell precursor cells, allowing for the study of erythropoiesis in a controlled environmentErythropoietin-MimeticPeptide17 (EMP17). .50. Details Quick View. Placeholder ·EMP17, FITC-LC labeled. 8.90 – 0.10 Price range: 8.90 through ....

* Develop Novel Therapeutics: While not a therapeutic drug itself, the understanding gained from studying EMP17 could contribute to the development of new drugs aimed at treating conditions characterized by low red blood cell counts, such as anemia.

* Explore Other Biological Roles: Beyond erythropoiesis, research has also explored the involvement of EMP17-related proteins in other cellular processes. For example, a study identified a PPR-DYW protein named Empty pericarp17 (EMP17) that is required for C-to-U editing and kernel development in plants, highlighting the diverse functions proteins with similar nomenclature can have.Erythropoietin Receptor Beads: Comprehensive isolation ... This particular plant protein, EMP17, is localized in mitochondria and is involved in RNA editing.Signal Transduction Peptides Archives

Where to Find EMP17 Peptide

EMP17 peptide is commercially available from various scientific suppliersErythropoietin-Mimetic Peptide 17 (EMP17). These suppliers typically offer it in small quantities, such as 1 mg, 5 mg, 10 mg, 50 mg, 100 mg, or even 1g, catering to laboratory research needs. When purchasing, researchers should note the catalog number, manufacturer, and purity of the peptide.Erythropoietin-MimeticPeptide17 (EMP17). .50. Details Quick View. Placeholder ·EMP17, FITC-LC labeled. 8.90 – 0.10 Price range: 8.90 through ... Some common catalog numbers associated with EMP17 include AS-60180-1 and AS-64437. The price of EMP17 peptide can vary significantly based on the supplier, quantity, and purity, ranging from around €122.00 to €204.00 for a 1 mg tube, with other price ranges indicated such as $80 or a price range of $108Erythropoietin MimeticPeptide-1. CAS Number: 186526-28-3. Category:peptides. Synonyms:PeptideEMP1; glycylglycyl-L-threonyl-L-tyrosyl-L-seryl-L-cysteinyl-L ....90 through $430.10 for the labeled versionTube of EMP17 peptide Tube of EMP17 peptide.

Important Considerations and Related Concepts

It is crucial to distinguish EMP17 peptide from therapeutic erythropoietic agents used in clinical settings. While EMP17 mimics EPO's action, it is primarily a research tool. The use of erythropoietic agents and the elderly is a clinical consideration for treating anemia, and these are distinct from research peptides like EMP17.Kelowna International Scientific Inc Discussions around EMP17 benefits are generally within the context of scientific research and understanding biological mechanisms.Safety Data Sheet (SDS) Concerns regarding EMP17 dosage are relevant if it were to be considered for any application beyond laboratory research, and potential side effects such as autoimmune-mediated refractory anemia are serious considerations in the broader context of EPO-related therapies.(C) The subcellular localization ofEMP17. The 140 amino acids fragment from the N-terminus ofEMP17was fused with green fluorescence protein (EMP17N140:GFP) and transiently expressed in Arabidopsis protoplasts.

The broader family of peptides and peptides encompasses a vast array of biologically active molecules, and EMP17 is one example within this category. Other related peptides and peptidomimetics are continuously being developed and studied for various research and therapeutic purposes.PPR-DYW Protein EMP17 Is Required for Mitochondrial ... The field of peptide synthesis and application is rapidly advancing, with ongoing research into new peptides and their potential applications.

In summary, emp17 peptide is a significant synthetic tool for researchers investigating the complex pathways of erythropoiesis and EPO receptor signaling. Its precise chemical structure, availability in various forms, and commercial accessibility make it an indispensable resource for advancing our understanding of these critical biological processes.Erythropoietin-Mimetic Peptide 17 (EMP17)